Thursday 12 May 2016

Central Nervous System Medicines

An assignment given by a person named Hassan from England. He gets his work without paying and cheats his university. 


Non opioids for pain
c,d,g



Weak opioids for persisting pain
a,f


Strong opioids for severe pain
b,e

 






                                               


                               




Look at the following ladder for pain management:                                       
1)Which of the following drugs would you place on the bottom rung of the ladder (non opioids for pain)? (P9)
a) Codeine
b) Oxycodone
c) Ibuprofen
d) Paracetamol
e) Morphine
f) Dihydrocodeine
g) Aspirin

2)Which of the following drugs would you place on the middle rung of the ladder (weak opioids for pain)? (P9)
a) Codeine
b) Oxycodone
c) Ibuprofen
d) Paracetamol
e) Morphine
f) Dihydrocodeine
g) Aspirin



3)Which of the following drugs would you place on the top rung of the ladder (strong opioids for severe pain)? (P9)
a) Codeine
b) Oxycodone
c) Ibuprofen
d) Paracetamol
e) Morphine
f) Dihydrocodeine
g) Aspirin

For questions 4-7, put ticks in the appropriate boxes to show the actions of the following analgesics: (P9)

Analgesic
Reduces pain
Reduces fever
Reduces swelling
Thins the blood
Q4) Aspirin
ü   


ü   
Q5) Ibuprofen

ü   
ü   

Q6) Codeine
ü   



Q7) Paracetamol

ü   


8) Which of the following analgesics commonly causes drowsiness? (P10)
a) Aspirin
b) Ibuprofen
c) Codeine
d) Paracetamol

9) Which of the following analgesics might cause gastro intestinal bleeding? (P10)
a) Aspirin
b) Ibuprofen
c) Codeine
d) Paracetamol

10) Which of the following analgesics might trigger asthma? (P10)
a) Aspirin
b) Ibuprofen
c) Codeine
d) Paracetamol







11) An elderly patient asks about taking aspirin for her headache. What would you recommend and why? (P11)
Aspirin may cause bleeding in the small intestine, stomach, and brain in elder people; therefore the patient would be recommended to avoid prolonging the aspirin use. The reason is because of the fragility of blood vessel in old age. And thus, if any such complication develops, he should immediately stop taking aspirin and report about it.

12) A patient is suffering from mild to moderate pain following a back operation. What analgesic and dose could you recommend to this patient? (P9)
 Codeine or dihydrocodeine would be prescribed for mild to moderate pain for this patient. Either of the analgesic would be given in a dose of 60 mg.
13) List 3 possible side effects of the analgesic chosen in your previous answer and explain anything you would need to counsel the patient about (P10 and P11)
The side effects of dihydrocodeine include:
·         Constipation
·         Drowsiness
·         Dry mouth
In order to avoid these side effects, a patient will counsel to use it for a short time period because if used for a long duration, dependence may occur.
14) What drug and dose could the patient be stepped up to if the initial analgesic does not control the pain? (P9)
In case of initial analgesic fails to provide a relief, weak opioids are administered and if it still fails then strong opioids are given.
15) Why might temazepam be given as a pre-medication before an operation?

a) For legal reasons
b) For pain relief
c) To decrease anxiety, alleviate fear and produce a state of calmness. 
d) To produce respiratory depression


16) Which of the following are often used in intravenous general anaesthesia? [select all that apply]

a) Nitrous oxide
b) Thiopental sodium
c) Benzocaine
d) Propofol

17) A Patient is undergoing surgery. As part of the anaesthetic they were administered with 5mg of Alfentanil over 10 minutes followed by a maintenance dose of 50mcg/minute by intravenous infusion.
What is the purpose of the drug?
a) To prevent salivary excretions
b) Muscle relaxant
c) Opioid analgesic for pain relief
d) Inductions and maintenance of anaesthesia



18) The patient was also given 5mg of Mivacurium followed by a maintenance dose of 700mcg/minute by intravenous infusion.

What is the purpose of the drug?

a) Muscle relaxant
b) Inductions and maintenance of anaesthesia
c) To prevent salivary excretions
d) Opioid analgesic for pain relief

19) Why are combinations of drugs used in general anaesthesia?
Propofol, Morphine, halothane or nitric oxide, succinylcholine, etc are some of the drugs combination used in general anaesthesia.

20) Local anaesthesia involves:

a) Putting the patient into an unconscious state - strong analgesics and paralysis agents are also used for major surgery
b) The numbing of a small area of the body but the patient is put into an unconscious state
c) The numbing of a small area of the body in which the patient remains conscious – strong analgesics and paralysis agents are used for safety
d) The numbing of a small area of the body and the patient remains conscious for minor surgery

21) Which one of the following is false regarding local anaesthesia?
a) The patient does not have to spend a night in hospital
b) The recovery time will be greater than general having a general anaesthetic
c) The individual does not have to undergo treatment with several drugs
d) They can be given through various routes

22) Topical anaesthetics are (select those that apply):
a) Invasive
b) Used for simple pain relief
c) Available OTC
d) Used during childbirth and major surgery

23) An epidural anaesthetic (select those that apply):
a) Provides complete pain relief without making you feel drowsy
b) Is used during childbirth and major surgery
c) Causes the patient to fall unconscious
d) Is suitable for patients with back problems

24) Discuss the difference between topical and epidural anaesthesia. Include when they are used, how they are administered and give two advantages and two disadvantages of both.
Epidural anaesthesia is basically administered in order to keep offer anaesthesia for several major surgeries of the limbs, abdominal and hips region. This anaesthesia is given at the epidural space of the spinal cord in the back area. On the other hand, local anaesthesias can be given at a variety of places for only minor procedures. The local anaesthesia provides regional nerve block. 
Advantages
Epidural anaesthesia 
1)      Epidural anaesthesia is required in a very less dose compared to general anaesthesia. 
2)      It serves as an excellent way to manage labour pain and delivery.
Local Anaesthesia
1)      It has an ability to provide numbness of a particular region of the body without affecting the level of consciousness of a patient.
2)      Patients recover faster.
Disadvantages
Epidural anaesthesia 
1)      Headache may occur in several patients who receive this type of anaesthesia.
2)      It may lower the blood pressure.
Local Anaesthesia
1)      Sometimes, local anaesthesia takes time to produce anaesthesia, like it may take up to 30 minutes in numbing the area where it is administered.

2)      It may not prove to be effective occasionally and thus may need additional anesthesia. 

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