A recent review published
by the Pain and Therapy journal found cannabinoids to be a likely favourable
adjunctive or replacement for opioids for diverse forms of acute and chronic
pain. According to it, cannabinoids have yielded positive results in various
trials over opioids, particularly for neuropathic pain. It has been
demonstrated to alleviate chronic pain in the elderly population and to result
in the discontinuation of opioids medications. The review also found
cannabinoids have a lower side-effect profile than opioids and may be used in
tandem with opioids to produce more powerful analgesia.
A survey by
researchers from the United States reported that patients found cannabis use to
be a helpful adjunct and alternative to opioids in managing their chronic pain.
They also claimed to get the extra benefit of enhancing their ability to work
and quality of life.
The Tilray Observational Study from
Canada gives an individual-level insight on cannabinoids substitution for
opioids and other prescribed medicines, along with the resulting improvement in
quality of life over a 6-month period. According to this study, the use of
cannabis for chronic pain can result in a reduction in opioid use and its
subsequent harmful effects. This has the potential to improve patient quality
of life and general public health.
Cannabis consists of various
biologically active molecules that can influence pain physiology. Comprehensive
reviews of the
literature support the potential safety and pain-relieving efficacy of
cannabinoids for chronic pain. The beneficial effects appear to peak after
three months of frequent cannabis use. Another study has
claimed to decrease the illicit use of opioids for chronic pain as well as
fentanyl exposure rates.
Microdosing CBD is a method of
consuming very small doses of cannabidiol on a daily basis. In a randomised
control trial, a
significant decline in pain intensity was observed with a dose of 0.5mg to 1mg
of cannabis in 27 patients with chronic neuropathic pain. The trial concluded
that people can benefit from cannabis-based treatments for their chronic pain.
A retrospective
evaluation found a low dose of cannaboids helpful in reducing chronic
pain, post-traumatic stress disorder-related insomnia, self-harm and nightmares
in inmates with serious mental illness. It can be useful in reducing emotional
exhaustion, anxiety, and burnout.
For a new cannabis user,
microdosing can be an excellent starting point. The goal of microdosing
marijuana is to achieve the desired impact throughout the day with a few
repeated doses instead of one huge dose.
Microdosing of marijuana can be
carried out via various forms like tinctures, gummies, pastilles, etc.
0 comments:
Post a Comment